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It was discovered that naltrexone and bupropion combined, which may be marketed in the foreseeable future as Contrave, give better weight loss results than dieting and exercise alone. Using two separate drugs to lose weight naturally can be very effective there are combinations while watching FDA now awaiting approval. When dealing with weight loss and the those who go through it you ought to err assisting caution and allow the FDA do its job and demand some research be done so the public recognizes the side effects and hazards of the medications before we drive them. Keep in mind that drug companies are in business to earn money and that they would say everything to keep people on their medications. Researchers found out that participants investing in this drug for a year, dropped excess weight within a month and have kept the extra weight off through the 56 weeks from the study. Contrave is often a combination in the drugs naltrexone and bupropion, which usually reflect a whole new trend of weight-loss drugs which might be made up of many active ingredient, that might make them more effective and safer. Combo-pilling is the newest fad or also the newest in the future under scrutiny and thus it is just more publicly known in recent months, comb-pilling to lose weight has been around since the eighties. The biggest reason that using a combination of pills has become popular may be the fact that since right now there are no long term prescription diet pills that have been approved by the FDA apart from orlistat. The truly disturbing part is doctors are prescribing these combinations of medications although some people might of the combinations happen to be rejected or have yet to be authorized by the FDA. Seizures can be a side effect with Contrave and really should not be taken in people with seizure disorders. The drug could also raise hypertension and heart rate, and shouldn't be used in people who have a history of cardiac arrest or stroke in the earlier six months. Blood pressure and pulse should also be measured prior to starting the drug and throughout therapy with all the drug. The FDA also warned that Contrave can raise blood pressure and heartrate and must stop used in patients with uncontrolled high hypertension, in addition to by anyone with heart-related and cerebrovascular (blood vessel dysfunction impacting the brain) disease. Patients which has a history of heart attack or stroke in the last six months, life-threatening arrhythmias, or congestive heart failure were excluded through the clinical trials. Those taking Contrave must have their heart-rate and pulse monitored regularly. In addition, because the compound includes bupropion, Contrave comes using a boxed warning to alert health care professionals and patients towards the increased likelihood of suicidal thoughts and behaviors linked to antidepressant drugs. The warning also notes that serious neuropsychiatric events happen to be reported in patients taking bupropion for quitting smoking. An independent report published by Gant Daily in April also stated that naltrexone also utilizes kleptomaniacs and gambling addicts, as well. Citing research from the University of Minnesota School of Medicine, Gant Daily reported the drug creates kleptomaniacs and chronic gamblers in the same way with alcohol and opioid addicts'by blocking the results of endorphins, which the brain releases when experiencing craving or compulsions.