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An article published on The American Journal on Addictions stated that expecting mothers who were dependent on opioids were strongly interested in antagonist treatment, especially the one that involves the usage of naltrexone to combat their alcohol abuse disorder. Using two separate drugs to shed weight can be very effective you will find combinations while watching FDA now awaiting approval. When dealing with weight reduction and the individuals who go through it you ought to err on the side of caution and allow the FDA do its job and demand some investigation be done so your public knows the side effects and hazards of the medications before we take them. Keep in mind that drug companies have been in business to generate income and that they would say almost anything to keep people on his or her medications. Researchers discovered that participants investing in this drug for a year, dropped excess weight within four weeks and have kept the weight off through the 56 weeks with the study. Contrave is often a combination of the drugs naltrexone and bupropion, which appears to reflect a new trend of weight-loss drugs that are made up of several active ingredient, that might make them more potent and safer. Combo-pilling may be the newest fad or also the newest to come under scrutiny and thus it is just more publicly known recently, comb-pilling for losing weight has been around since the eighties. The biggest reason that by using a combination of pills is becoming popular is the fact that since right now there aren't any long term prescription weightloss pills that have been authorized by the FDA other than orlistat. The truly disturbing part is always that doctors are prescribing these combinations of medications even though some of the combinations are actually rejected or have yet to be approved by the FDA. Seizures really are a side effect with Contrave and really should not be taken in people who have seizure disorders. The drug can also raise blood pressure levels and heartbeat, and mustn't be used in those with a history of cardiac arrest or stroke in the earlier six months. Blood pressure and pulse should also be measured before commencing the drug and throughout therapy with the drug. The FDA also warned that Contrave can raise blood pressure level and heartrate and must stop used in patients with uncontrolled high hypertension, and also by you aren't heart-related and cerebrovascular (circulation dysfunction impacting the mind) disease. Patients using a history of cardiac event or stroke in the previous six months, life-threatening arrhythmias, or congestive heart failure were excluded from the clinical trials. Those taking Contrave must have their heart-rate and pulse monitored regularly. In addition, because the compound includes bupropion, Contrave comes using a boxed warning to alert medical researchers and patients to the increased probability of suicidal thoughts and behaviors related to antidepressant drugs. The warning also notes that serious neuropsychiatric events have been reported in patients taking bupropion for quitting smoking. The most common unwanted side effects with Contrave include nausea, constipation, headache, vomiting, dizziness, insomnia, dry mouth, and diarrhea.